Quantitative Systems Pharmacologist (FSP)
求人ID R0000032536 Category Clinical TrialsAbout this Role
Quantitative Systems Pharmacologist
KEY RESPONSIBILITIES:
The Quantitative Systems Pharmacologist is responsible for the development and application of QSP models for the in silico evaluation of novel targets and compounds, including preclinical and clinical study design and mechanistic interpretation of results. This individual integrates and shares data and knowledge in a highly stimulating, collaborative, and multi-disciplinary environment to develop a quantitative understanding of physiological systems and disease mechanisms within and across therapeutic areas.
Minimum Requirements
1,Provides pharmacometric expertise and leadership to projects.
2,Develops model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision-making, in collaboration with partners.
3,Conducts and reports quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development.
4,Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety.
5,Acts as pharmacometric Subject Matter Expert (SME), including proactive support and development of quantitative methodology, software, hardware, and related business processes, in addition to training to the the global clinical pharmacology organization.
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